◎ CONQIRA

Editorial summaries

Provisional editorial interpretation based on a selected group of reviewed publications. This is not a systematic review of the entire catalogue or a scientific consensus statement.

Editorial summary translated for navigation; original publication language is unchanged.

Experimental and theoretical approaches to conscious processing

Stanislas Dehaene; Jean-Pierre Changeux · 2011 · Neuron

Editorial summary

Reviews conscious access through amplification and widespread availability of neural information in the global neuronal workspace framework.

Limitations

A theoretical synthesis does not fully explain subjective experience.

Open source

Conscious Processing and the Global Neuronal Workspace Hypothesis

George A. Mashour et al. · 2020 · Neuron

Editorial summary

Reviews global neuronal workspace mechanisms across perception, attention, working memory and anesthesia, emphasizing recurrent amplification and information sharing.

Limitations

Competing theoretical accounts remain under investigation.

Open source

Integrated information theory (IIT) 4.0: Formulating the properties of phenomenal existence in physical terms

Larissa Albantakis et al. · 2023 · PLOS Computational Biology

Editorial summary

Formalizes integrated information theory using proposed properties of experience, intrinsic information and causal relationships within physical systems.

Limitations

The framework is theoretical, not experimental proof of consciousness.

Open source

Neural correlates of consciousness: progress and problems

Christof Koch; Marcello Massimini; Melanie Boly; Giulio Tononi · 2016 · Nature Reviews Neuroscience

Editorial summary

Reviews neural correlates and quantitative measures, emphasizing posterior cortical regions and separating experience from task monitoring and reporting.

Limitations

Correlation does not establish causal sufficiency or settle theoretical disagreements.

Open source

A theoretically based index of consciousness independent of sensory processing and behavior

Adenauer G. Casali et al. · 2013 · Science Translational Medicine

Editorial summary

Introduces an index of stimulation-evoked EEG complexity that distinguished several conscious and unconscious conditions in the studied participants.

Limitations

A physiological index does not directly reveal subjective experience.

Open source

Stratification of unresponsive patients by an independently validated index of brain complexity

Silvia Casarotto et al. · 2016 · Annals of Neurology

Editorial summary

Validated a brain-complexity threshold before identifying some unresponsive patients with values overlapping those measured in conscious benchmark conditions.

Limitations

High complexity cannot independently confirm experience in noncommunicative patients.

Open source

Adversarial testing of global neuronal workspace and integrated information theories of consciousness

Cogitate Consortium; Oscar Ferrante et al. · 2025 · Nature

Editorial summary

A preregistered multimodal study in 256 participants challenged selected predictions of global neuronal workspace and integrated information theories.

Limitations

It tests specific visual-consciousness predictions, not every claim of either theory.

Open source

Breakdown of cortical effective connectivity during sleep

Marcello Massimini et al. · 2005 · Science

Editorial summary

Magnetic stimulation and EEG showed that cortical responses during non-REM sleep remained more localized than during quiet wakefulness.

Limitations

These findings do not imply that all sleep lacks conscious experience.

Open source

Consciousness and Complexity during Unresponsiveness Induced by Propofol, Xenon, and Ketamine

Simone Sarasso et al. · 2015 · Current Biology

Editorial summary

During drug-induced unresponsiveness, ketamine preserved more complex cortical responses than propofol or xenon, separating responsiveness from brain complexity.

Limitations

Drug effects and retrospective reports complicate inferences about subjective experience.

Open source

The neural correlates of dreaming

Francesca Siclari et al. · 2017 · Nature Neuroscience

Editorial summary

High-density EEG associated reported dreams with reduced posterior low-frequency activity, while some faster activity correlated with dream contents.

Limitations

Reports after awakening may confound dreaming with dream recall.

Open source

Detecting awareness in the vegetative state

Adrian M. Owen et al. · 2006 · Science

Editorial summary

In one behaviorally unresponsive patient, instructed mental imagery produced task-specific brain activity resembling healthy volunteers, revealing covert command-following.

Limitations

A single-patient finding cannot establish awareness in all similarly diagnosed patients.

Open source

Preserved feedforward but impaired top-down processes in the vegetative state

Melanie Boly et al. · 2011 · Science

Editorial summary

During an auditory task, impaired backward frontal-to-temporal connectivity distinguished the vegetative-state group from controls in the studied sample.

Limitations

Model-dependent connectivity estimates are not universally sufficient markers of consciousness.

Open source

Near-death experience in survivors of cardiac arrest: a prospective study in the Netherlands

Pim van Lommel et al. · 2001 · The Lancet

Editorial summary

Interviews with 344 cardiac-arrest survivors examined near-death experiences and subsequent attitude changes.

Limitations

Recalled experiences cannot establish their timing or independence from brain activity.

Open source

A qualitative and quantitative study of the incidence, features and aetiology of near death experiences in cardiac arrest survivors

Sam Parnia et al. · 2001 · Resuscitation

Editorial summary

Interviews with 63 cardiac-arrest survivors explored memories, experience features and physiological associations.

Limitations

Few reported experiences, limiting statistical conclusions and physiological interpretation.

Open source

AWARE-AWAreness during REsuscitation-a prospective study

Sam Parnia et al. · 2014 · Resuscitation

Editorial summary

This multicentre study examined memories after cardiac arrest, with 140 initial and 101 detailed survivor interviews.

Limitations

Survivor selection and few awareness reports limit generalization.

Open source

AWAreness during REsuscitation - II: A multi-center study of consciousness and awareness in cardiac arrest

Sam Parnia et al. · 2023 · Resuscitation

Editorial summary

Interviews and physiological monitoring explored awareness during resuscitation; none of 28 interviewed survivors identified the visual target.

Limitations

Small survivor samples cannot establish consciousness after irreversible death.

Open source

Surge of neurophysiological coherence and connectivity in the dying brain

Jimo Borjigin et al. · 2013 · Proceedings of the National Academy of Sciences

Editorial summary

Rat EEG showed briefly increased gamma coordination and connectivity after experimental cardiac arrest.

Limitations

Animal neural signals do not directly demonstrate subjective experience.

Open source

Enhanced Interplay of Neuronal Coherence and Coupling in the Dying Human Brain

Raul Vicente et al. · 2022 · Frontiers in Aging Neuroscience

Editorial summary

EEG recorded gamma activity and coupling changes around cardiac arrest in one brain-injured patient.

Limitations

A single injured brain cannot establish conscious experience.

Open source

Surge of neurophysiological coupling and connectivity of gamma oscillations in the dying human brain

Gang Xu et al. · 2023 · Proceedings of the National Academy of Sciences

Editorial summary

Two of four dying patients showed increased gamma activity and connectivity after ventilatory support withdrawal.

Limitations

No subjective reports linked these signals to conscious awareness.

Open source

Return of consciousness during ongoing cardiopulmonary resuscitation: A systematic review

Alexander Olaussen et al. · 2015 · Resuscitation

Editorial summary

This systematic review gathered reports of signs of consciousness during ongoing cardiopulmonary resuscitation.

Limitations

Responsiveness during CPR is not evidence of consciousness after irreversible death.

Open source

Consciousness and the Dying Brain

George A. Mashour et al. · 2024 · Anesthesiology

Editorial summary

This review connects near-death reports with research on electrical activity and connectivity around cardiac or respiratory arrest.

Limitations

Candidate neural correlates do not establish subjective experience.

Open source

Near-death experiences after cardiac arrest: a scoping review

Joshua G. Kovoor et al. · 2024 · Discover Mental Health

Editorial summary

This scoping review mapped prospective studies, finding varied experience frequencies and assessment methods.

Limitations

Heterogeneity and recall bias limited comparison and prevented meta-analysis.

Open source

Electromagnetic signals are produced by aqueous nanostructures derived from bacterial DNA sequences

Luc Montagnier et al. · 2009 · Interdisciplinary Sciences: Computational Life Sciences

Editorial summary

The authors report electromagnetic signals in diluted bacterial DNA preparations and propose a resonance mechanism.

Limitations

Independent replication is not established by this abstract.

Open source

Biophoton emission. New evidence for coherence and DNA as source

F. A. Popp et al. · 1984 · Cell Biophysics

Editorial summary

Cellular photon measurements were interpreted by the authors as evidence for coherence and a contribution from DNA.

Limitations

A 2015 critical review challenges the coherence interpretation.

Open source

[Experimental investigations on ultraweak photonemission form biological systems (author's transl)]

B. Ruth and F. A. Popp · 1976 · Zeitschrift für Naturforschung C

Editorial summary

Measurements detected faint photon emission from yeast and seedlings, including changes after chemical treatment.

Limitations

Light emission alone does not demonstrate communication or consciousness.

Open source

Photon emission from perturbed and dying organisms: biomedical perspectives

Janusz Slawinski · 2005 · Forschende Komplementärmedizin und Klassische Naturheilkunde

Editorial summary

This review relates biological photon emission to metabolism, physiological stress and biochemical excitation processes.

Limitations

It does not demonstrate consciousness surviving death.

Open source

Ultra-weak photon emission from biological samples: definition, mechanisms, properties, detection and applications

Michal Cifra and Pavel Pospíšil · 2014 · Journal of Photochemistry and Photobiology B: Biology

Editorial summary

The review explains oxidative sources of cellular light and surveys detection methods and physiological monitoring applications.

Limitations

Emission evidence does not establish optical communication or conscious experience.

Open source

Biophotons, coherence and photocount statistics: A critical review

Michal Cifra et al. · 2015 · Journal of Luminescence

Editorial summary

This critical review finds biological light emission established, but reliable evidence for coherence or nonclassical photon statistics lacking.

Limitations

The assessment covers literature available in 2015.

Open source

Integrating information in the brain's EM field: the cemi field theory of consciousness

Johnjoe McFadden · 2020 · Neuroscience of Consciousness

Editorial summary

The cemi model proposes consciousness as information integrated in the brain’s electromagnetic field and outlines testable predictions.

Limitations

A theoretical proposal is not conclusive experimental confirmation.

Open source

Consciousness: Matter or EMF?

Johnjoe McFadden · 2023 · Frontiers in Human Neuroscience

Editorial summary

This theoretical review advocates electromagnetic accounts of consciousness and compares their explanatory claims with neuronal theories.

Limitations

The comparisons represent the author’s position, not independent confirmation.

Open source

Ultra weak photon emission—a brief review

Rhys R. Mould et al. · 2024 · Frontiers in Physiology

Editorial summary

The authors survey biological photon research, metabolic origins, detection methods and potential applications of ultraweak light emission.

Limitations

Proposed biological roles and applications require separate validation.

Open source

Ultra-weak photon emission: from oxidative metabolism to DNA-based communication: a review of biochemical, biophysical and quantum biological perspectives

Jozsef Bodis et al. · 2026 · Frontiers in Endocrinology

Editorial summary

A review with mouse-embryo measurements examines metabolic photon sources and hypotheses about DNA-related optical signalling.

Limitations

The authors acknowledge that DNA-based biophoton communication remains unproven.

Open source

Ultra-Weak Photon Emission as a By-Product of Mitochondrial Oxidative Metabolism: Mechanisms, Limits, and Implications

Samuel Crowther, Alice Attenborough and Frank Vollmer · 2026 · Nanophotonics

Editorial summary

The review explains mitochondrial photon emission through oxidative chemistry, distinguishing baseline emission from stress-related increases.

Limitations

Its energetic analysis does not cover every cellular light source.

Open source

Imaging of ultraweak spontaneous photon emission from human body displaying diurnal rhythm

Masaki Kobayashi, Daisuke Kikuchi and Hitoshi Okamura · 2009 · PLOS ONE

Editorial summary

Sensitive cameras visualized faint human-body light emission and changes in its intensity across the day.

Limitations

These measurements do not demonstrate an aura or consciousness signal.

Open source

Consciousness in the universe: a review of the 'Orch OR' theory

Stuart Hameroff; Roger Penrose · 2014 · Physics of Life Reviews

Editorial summary

Reviews the proposed connection between consciousness, quantum processes in microtubules and objective reduction.

Limitations

A theoretical proposal, not a demonstration that quantum processes generate consciousness.

Open source

Importance of quantum decoherence in brain processes

Max Tegmark · 2000 · Physical Review E

Editorial summary

Calculates rapid decoherence in brain models and challenges a quantum-computational explanation of cognition.

Limitations

The conclusions depend on the modeled states and physical assumptions.

Open source

Quantum computation in brain microtubules: decoherence and biological feasibility

S. Hagan; S. R. Hameroff; J. A. Tuszyński · 2002 · Physical Review E

Editorial summary

Recalculates microtubule decoherence under different assumptions, responding to criticisms of the Orch OR model.

Limitations

Model calculations do not establish conscious quantum computation in living brains.

Open source

Microtubule-Stabilizer Epothilone B Delays Anesthetic-Induced Unconsciousness in Rats

Sana Khan et al. · 2024 · eNeuro

Editorial summary

A microtubule-stabilizing treatment delayed loss of righting reflex during isoflurane anesthesia in rats.

Limitations

An animal behavioral measure does not directly demonstrate quantum consciousness.

Open source